Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic susceptibility to autoimmunity-Current status and challenges.

Advances in immunology - 1 Jan 2022

Huang Miaozhen, Xu Huji

Abstract excerpt

Autoimmune diseases (ADs) often arise from a combination of genetic and environmental triggers that disrupt the immune system's capability to properly tolerate body self-antigens. Familial studies provided the earliest insights into the risk loci of such diseases, while genome-wide association studies (GWAS) significantly broadened the horizons. A drug targeting a prominent pathological pathway can be applied to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune Diseases
Share to Autoimmunity
Share to COVID-19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Source

Identifiers

PMID: 36410874
DOI: 10.1016/bs.ai.2022.08.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic susceptibility to autoimmunity-Current status and challenges.PMID 36410874Read ↗

Innate and adaptive immune abnormalities underlying autoimmune diseases: the genetic connections.Semantic proximity Read ↗

Genetic susceptibility to autoimmune diseases.Semantic proximity Read ↗

The genetics of human autoimmune disease.Semantic proximity Read ↗

What is next after the genes for autoimmunity?Semantic proximity Read ↗

Recent advances in the genetics of autoimmune disease.Semantic proximity Read ↗

Genetic predisposition to autoimmunity--what have we learned?Semantic proximity Read ↗

Human genetics offers an emerging picture of common pathways and mechanisms in autoimmunity.Semantic proximity Read ↗

Common genetic factors among autoimmune diseases.Semantic proximity Read ↗

Identifying genetic determinants of autoimmunity and immune dysregulation.Semantic proximity Read ↗

Rare autoimmune disorders with Mendelian inheritance.Semantic proximity Read ↗

Host Genetics at the Intersection of Autoimmunity and COVID-19: A Potential Key for Heterogeneous COVID-19 Severity.Semantic proximity Read ↗

The genetics of shared autoimmunity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.