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Host Genetics at the Intersection of Autoimmunity and COVID-19: A Potential Key for Heterogeneous COVID-19 Severity.

Frontiers in immunology - 1 Jan 2020

Karaderi Tugce, Bareke Halin, Kunter Imge, Seytanoglu Adil, Cagnan Ilgin, Balci Deniz, Barin Burc, Hocaoglu Mevhibe B, Rahmioglu Nilufer, Asilmaz Esra, Taneri Bahar

Abstract excerpt

COVID-19 presentation is very heterogeneous across cases, and host factors are at the forefront for the variables affecting the disease manifestation. The immune system has emerged as a key determinant in shaping the outcome of SARS-CoV-2 infection. It is mainly the deleterious unconstrained immune response, rather than the virus itself, which leads to severe cases of COVID-19 and the associated mortality....

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Identifiers

PMID: 33414783
DOI: 10.3389/fimmu.2020.586111
PMCID: PMC7783411

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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