Article
Innate and adaptive immune abnormalities underlying autoimmune diseases: the genetic connections.
Science China. Life sciences - 1 Jul 2023
Chi Xinxin, Huang Miaozhen, Tu Hailin, Zhang Bin, Lin Xin, Xu Huji, Dong Chen, Hu Xiaoyu
Abstract excerpt
With the exception of an extremely small number of cases caused by single gene mutations, most autoimmune diseases result from the complex interplay between environmental and genetic factors. In a nutshell, etiology of the common autoimmune disorders is unknown in spite of progress elucidating certain effector cells and molecules responsible for pathologies associated with inflammatory and tissue damage. In...
Topics
- Humans
- Autoimmune Diseases
- Immunity, Innate
- Autoimmunity
- Adaptive Immunity
- Genetic Predisposition to Disease