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Article

The association of arterial stiffness index with cerebrovascular and cardiometabolic disease: A Mendelian randomization study.

International journal of stroke : official journal of the International Stroke Society - 1 Dec 2022

Liu Weishi, Zhang Luyang, Gao Yuan, Liu Kai, Li Yanan, Liu Chen, Yan Yingxue, Liu Hongbing, Li Shen, Fang Hui, Song Bo, Xia Zongping, Xu Yuming

Abstract excerpt

BACKGROUND: Arterial stiffness index (ASI) is a potential risk factor for cerebrovascular and cardiometabolic diseases, but the causal links between them are inconclusive. The aim is to evaluate the causal effects of ASI on cerebrovascular and cardiometabolic diseases by Mendelian randomization (MR). METHODS: Two-sample MR analysis was performed to infer causal links. Genetic variants significantly associated...

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PMID: 36408634
DOI: 10.1177/17474930211066432

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