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Article

Toward defining the immunogenicity of HLA epitopes: Impact of HLA class I eplets on antibody formation during pregnancy.

HLA - 1 Nov 2020

Hönger Gideon, Niemann Matthias, Schawalder Lara, Jones James, van Heck Michelle R, van de Pasch Loes A L, Vendelbosch Sanne, Rozemuller Erik H, Hösli Irene, Blümel Sarah, Schaub Stefan

Abstract excerpt

Eplets are functional units of structural epitopes on donor HLA, potentially recognized by complementarity-determining regions of the paratope of the recipients' B-cell receptors or antibodies (Ab). Their individual immunogenicity is poorly described, yet this feature would be of clinical importance for pretransplant risk assessment. The aim of this study was to determine the relative immunogenicity of HLA class...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32829523
DOI: 10.1111/tan.14054

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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