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Article

Identifying inflammatory phenotypes to target mechanism-specific treatments in sepsis.

Cell reports. Medicine - 15 Nov 2022

Gómez Hernando, Anderko Renee R, Carcillo Joseph A

Abstract excerpt

A clinical trial by Leventogiannis et al.1 suggests that ferritin and HLA-DR monocyte receptor expression can identify septic patients with macrophage-activation-like syndrome (MALS), or immunoparalysis, and that targeting IL-1ra treatment with this strategy may improve outcomes.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36384087
DOI: 10.1016/j.xcrm.2022.100823
PMCID: PMC9729868

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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