Stratified assessment of platelets in sepsis: from dynamic counts to functional phenotypes.

Abstract excerpt

Sepsis is a major global cause of critical illness with high mortality. Sepsis-associated thrombocytopenia (SAT) is linked to markedly increased death risk and is a key indicator of poor prognosis. Although platelets are recognized as central players in the "inflammation-coagulation-immunity" network, most studies emphasize platelet counts rather than functional heterogeneity and underlying regulatory mechanisms,...

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