Article
Immunophenotyping of Peripheral Blood Mononuclear Cells in Septic Shock Patients With High-Dimensional Flow Cytometry Analysis Reveals Two Subgroups With Differential Responses to Immunostimulant Drugs.
Frontiers in immunology - 1 Jan 2021
Wang Ya, Gloss Brian, Tang Benjamin, Dervish Suat, Santner-Nanan Brigitte, Whitehead Christina, Masters Kristy, Skarratt Kristen, Teoh Sally, Schibeci Stephen, Fewings Nicole, Brignone Chrystelle, Triebel Frederic, Booth David, McLean Anthony, Nalos Marek
Abstract excerpt
Sepsis is associated with a dysregulated inflammatory response to infection. Despite the activation of inflammation, an immune suppression is often observed, predisposing patients to secondary infections. Therapies directed at restoration of immunity may be considered but should be guided by the immune status of the patients. In this paper, we described the use of a high-dimensional flow cytometry (HDCyto) panel...
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