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Article

Mice lacking cyclin-dependent kinase-like 5 manifest autistic and ADHD-like behaviors

13 Jul 2017

Abstract excerpt

Neurodevelopmental disorders frequently share common clinical features and appear high rate of comorbidity, such as those present in patients with attention-deficit hyperactivity disorder (ADHD) and autism spectrum disorders (ASD). While characterizing behavioral phenotypes in the mouse model of cyclin-dependent kinase-like 5 (CDKL5) disorder, a neurodevelopmental disorder caused by mutations in the X-linked gene...

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PMID: 29016850
DOI: 10.1093/hmg/ddx279

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