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Article

The mutational spectrum of SARS-CoV-2 genomic and antigenomic RNA.

Proceedings. Biological sciences - 30 Nov 2022

Zhao Lele, Hall Matthew, de Cesare Mariateresa, MacIntyre-Cockett George, Lythgoe Katrina, Fraser Christophe, Bonsall David, Golubchik Tanya, Ferretti Luca

Abstract excerpt

The raw material for viral evolution is provided by intra-host mutations occurring during replication, transcription or post-transcription. Replication and transcription of Coronaviridae proceed through the synthesis of negative-sense 'antigenomes' acting as templates for positive-sense genomic and subgenomic RNA. Hence, mutations in the genomes of SARS-CoV-2 and other coronaviruses can occur during (and after)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36382519
DOI: 10.1098/rspb.2022.1747
PMCID: PMC9667359

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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