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Article

Mutational signatures and heterogeneous host response revealed via large-scale characterization of SARS-CoV-2 genomic diversity

2020-07-06

Abstract excerpt

<h4> A bstract </h4> To dissect the mechanisms underlying the inflation of variants in the SARS-CoV-2 genome, we present one of the largest up-to-date analyses of intra-host genomic diversity, which reveals that most samples present heterogeneous genomic architectures, due to the interplay between host-related mutational processes and transmission dynamics. The deconvolution of the set of intra-host minor varia...

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Literature Corpus work
fc8f2ba1-a3e2-568b-83bb-a9a52f50796d
DOI
10.1101/2020.07.06.189944
Open publication

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Mutational signatures and heterogeneous host response revealed via large-scale characterization of SARS-CoV-2 genomic diversityDOI 10.1101/2020.07.06.189944
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