Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-Wide Sequencing Identified Rare Genetic Variants for Childhood-Onset Monogenic Lupus.

The Journal of rheumatology - 1 May 2023

Misztal Melissa C, Liao Fangming, Couse Madeline, Cao Jingjing, Dominguez Daniela, Lau Lynette, Marshall Christian R, Naumenko Sergey, Knight Andrea M, Levy Deborah M, Hiraki Linda T

Abstract excerpt

OBJECTIVE: Genetics play an important role in systemic lupus erythematosus (SLE) pathogenesis. We calculated the prevalence of rare variants in known monogenic lupus genes among children suspected of monogenic lupus. METHODS: We completed paired-end genome-wide sequencing (whole genome sequencing [WGS] or whole exome sequencing) in patients suspected of monogenic lupus, and focused on 36 monogenic lupus genes. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exome Sequencing

Share to Genetic Predisposition to Disease

Share to Lupus Erythematosus, Systemic

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Share to Systemic Lupus Erythematosus Research

Source

Identifiers

PMID: 36379578
DOI: 10.3899/jrheum.220513

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-Wide Sequencing Identified Rare Genetic Variants for Childhood-Onset Monogenic Lupus.PMID 36379578Read ↗

Rare and common single nucleotide variants in childhood-onset systemic lupus erythematosusSemantic proximity Read ↗

Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosusSemantic proximity Read ↗

Whole exome sequencing in childhood-onset lupus frequently detects single gene etiologiesSemantic proximity Read ↗

Single-centre comparison of non-familial, familial and monogenic lupus.Semantic proximity Read ↗

Genetic determinants of childhood onset systemic lupus erythematosus.Semantic proximity Read ↗

Genetics of Systemic Lupus ErythematosusSemantic proximity Read ↗

Genetic landscape of early-onset systemic lupus erythematous in India.Semantic proximity Read ↗

Genetic screening of early-onset patients with systemic lupus erythematosus by a targeted next-generation sequencing gene panel.Semantic proximity Read ↗

Genomics of Systemic Lupus Erythematosus: Insights Gained by Studying Monogenic Young-Onset Systemic Lupus Erythematosus.Semantic proximity Read ↗

Monogenic lupus: Tracing the therapeutic implications from single gene mutations.Semantic proximity Read ↗

Review of recent genome-wide association scans in lupus.Semantic proximity Read ↗

Updates in Lupus Genetics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.