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Genetic screening of early-onset patients with systemic lupus erythematosus by a targeted next-generation sequencing gene panel.

Lupus - 1 Mar 2022

Dasdemir Selcuk, Yildiz Mehmet, Celebi Damla, Sahin Sezgin, Aliyeva Numune, Haslak Fatih, Gunalp Aybuke, Adrovic Amra, Barut Kenan, Artim Esen Bahar, Kasapcopur Ozgur

Abstract excerpt

OBJECTIVE: In this study, we aimed to screen 31 genes (C1QA, C1QB, C1QC, C1R, C1S, C2, C3, TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, DNASE1, DNASE1L3, PRKCD, ACP5, SLC7A7, IFIH1, TMEM173, ISG15, CYBB, FAS, FASLG, KRAS, NRAS, MAN2B1, PEPD, PTPN11, RAG2, and SHOC2), that we have categorized under the umbrella term "monogenic lupus" using a targeted next-generation sequencing (NGS) panel in 24 individuals...

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Identifiers

PMID: 35086391
DOI: 10.1177/09612033221076733

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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