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Article

The Thr105Ile Variant (rs11558538) of the Histamine N-methyltransferase Gene may be associated with Reduced Risk of Parkinson Disease: A Meta-analysis.

Genetic testing and molecular biomarkers - 1 Nov 2022

Lu Yongxia, Dong Cheng Zhen, Bao Dongmei, Zhong Chengqing, Liu Keting, Chen Lifan, Wang Wei, Yang Baiyuan

Abstract excerpt

Background: Previous studies have reported conflicting results regarding the potential association between the risk of Parkinson's disease (PD) and the single nucleotide polymorphism, rs11558538 (Thr105Ile), in the histamine N-methyltransferase (HNMT) gene. We performed a systematic review and meta-analysis to improve our understanding of the association between them. Methods: We systematically searched several...

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PMID: 36378841
DOI: 10.1089/gtmb.2021.0299

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Thr105Ile Variant (rs11558538) of the Histamine N-methyltransferase Gene may be associated with Reduced Risk of Parkinson Disease: A Meta-analysis.PMID 36378841Read ↗

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