Article
Nonsynonymous polymorphisms of histamine-metabolising enzymes in patients with Parkinson's disease.
Neuromolecular medicine - 1 Jan 2008
Agúndez José A G, Luengo Antonio, Herráez Oscar, Martínez Carmen, Alonso-Navarro Hortensia, Jiménez-Jiménez Félix Javier, García-Martín Elena
Abstract excerpt
OBJECTIVE: To analyze genetically based impairment in histamine-metabolising enzymes in patients with Parkinson's disease (PD). METHODS: Leukocytary DNA from 214 PD patients and a control group of 295 unrelated healthy individuals was studied for nonsynonymous histamine N-methyltransferase (HNMT)...
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