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Article

Colibactin possessing E. coli isolates in association with colorectal cancer and their genetic diversity among Pakistani population.

PloS one - 1 Jan 2022

Tariq Habiba, Noreen Zobia, Ahmad Aftab, Khan Laraib, Ali Mashhood, Malik Muhammad, Javed Aneela, Rasheed Faisal, Fatima Alina, Kocagoz Tanil, Sezerman Ugur, Bokhari Habib

Abstract excerpt

Colorectal cancer (CRC) is the third most prevalent cause of tumorigenesis and several pathogenic bacteria have been correlated with aggressive cases of cancer i.e., genotoxin (colibactin) producing Escherichia coli (E. coli). This study was designed to investigate the genetic diversity of clb+clb+ E. coli strains and their association with CRC. Pathogenic E. coli isolates from colorectal biopsies were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36367873
DOI: 10.1371/journal.pone.0262662
PMCID: PMC9651576

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