Article
Molecular Function and Contribution of TBX4 in Development and Disease.
American journal of respiratory and critical care medicine - 1 Apr 2023
Karolak Justyna A, Welch Carrie L, Mosimann Christian, Bzdęga Katarzyna, West James D, Montani David, Eyries Mélanie, Mullen Mary P, Abman Steven H, Prapa Matina, Gräf Stefan, Morrell Nicholas W, Hemnes Anna R, Perros Frédéric, Hamid Rizwan, Logan Malcolm P O, Whitsett Jeffrey, Galambos Csaba, Stankiewicz Paweł, Chung Wendy K, Austin Eric D
Abstract excerpt
Over the past decade, recognition of the profound impact of the TBX4 (T-box 4) gene, which encodes a member of the evolutionarily conserved family of T-box-containing transcription factors, on respiratory diseases has emerged. The developmental importance of TBX4 is emphasized by the association of TBX4 variants with congenital disorders involving respiratory and skeletal structures; however, the exact role of...
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