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Article

TBX4 variants and pulmonary diseases: getting out of the 'Box'.

Current opinion in pulmonary medicine - 1 May 2020

Haarman Meindina G, Kerstjens-Frederikse Wilhelmina S, Berger Rolf M F

Abstract excerpt

PURPOSE OF REVIEW: In 2013, the association between T-Box factor 4 (TBX4) variants and pulmonary arterial hypertension (PAH) has first been described. Now - in 2020 - growing evidence is emerging indicating that TBX4 variants associate with a wide spectrum of lung disorders. RECENT FINDINGS: TBX4 variants are enriched in both children and adults with PAH. The clinical phenotype associated with a TBX4 variant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32195678
DOI: 10.1097/MCP.0000000000000678
PMCID: PMC7170437

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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