Article
Progress and perspective of TBX6 gene in congenital vertebral malformations.
Oncotarget - 30 Aug 2016
Chen Weisheng, Liu Jiaqi, Yuan Dongtang, Zuo Yuzhi, Liu Zhenlei, Liu Sen, Zhu Qiankun, Qiu Guixing, Huang Shishu, Giampietro Philip F, Zhang Feng, Wu Nan, Wu Zhihong
Abstract excerpt
Congenital vertebral malformation is a series of significant health problems affecting a large number of populations. It may present as an isolated condition or as a part of an underlying syndromes occurring with other malformations and/or clinical features. Disruption of the genesis of paraxial mesoderm, somites or axial bones can result in spinal deformity. In the course of somitogenesis, the segmentation clock...
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