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Article

The Roles of MTRR and MTHFR Gene Polymorphisms in Colorectal Cancer Survival.

Nutrients - 1 Nov 2022

Wang Yu, Du Meizhi, Vallis Jillian, Shariati Matin, Parfrey Patrick S, Mclaughlin John R, Wang Peizhong Peter, Zhu Yun

Abstract excerpt

BACKGROUND: Paradoxically epidemiological data illustrate a negative relationship between dietary folate intake and colorectal cancer (CRC) risk. The occurrence and progression of CRC may be influenced by variants in some key enzyme coding genes in the folate metabolic pathway. We investigated the correlation between genetic variants in methionine synthase reductase (MTRR) and methylenetetrahydrofolate reductase...

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Identifiers

PMID: 36364857
DOI: 10.3390/nu14214594
PMCID: PMC9658674

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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