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Article

A Pan-Draft Metabolic Model Reflects Evolutionary Diversity across 332 Yeast Species.

Biomolecules - 3 Nov 2022

Lu Hongzhong, Kerkhoven Eduard J, Nielsen Jens

Abstract excerpt

Yeasts are increasingly employed in synthetic biology as chassis strains, including conventional and non-conventional species. It is still unclear how genomic evolution determines metabolic diversity among various yeast species and strains. In this study, we constructed draft GEMs for 332 yeast species using two alternative procedures from the toolbox RAVEN v 2.0. We found that draft GEMs could reflect the...

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PMID: 36358981
DOI: 10.3390/biom12111632
PMCID: PMC9687678

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