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Article

Historical contingency and the gradual evolution of metabolic properties in central carbon and genome-scale metabolisms.

BMC systems biology - 23 Apr 2014

Barve Aditya, Hosseini Sayed-Rzgar, Martin Olivier C, Wagner Andreas

Abstract excerpt

BACKGROUND: A metabolism can evolve through changes in its biochemical reactions that are caused by processes such as horizontal gene transfer and gene deletion. While such changes need to preserve an organism's viability in its environment, they can modify other important properties, such as a metabolism's maximal biomass synthesis rate and its robustness to genetic and environmental change. Whether such...

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PMID: 24758311
DOI: 10.1186/1752-0509-8-48
PMCID: PMC4022055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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