Article

Reconstruction of compartmentalized genome-scale metabolic models using deep learning for over 800 fungi

2023-08-24

Abstract excerpt

Eukaryotic metabolism is organized into subcellular compartments enclosed by lipid-membranes. Since most metabolites do not move freely across the membranes, the compartmentalization influences metabolic pathway connectivities. Thus, compartmentalizing the pathways also in genome-scale metabolic models (GEMs) is essential for accurate predictions of eukaryotic cells’ metabolic phenotypes. Compartmentalization has...

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Literature Corpus work: 0487ff51-ff35-5a46-99e4-1e409cc521b0
DOI: 10.1101/2023.08.23.554328

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