VSGs Expressed during Natural T. b. gambiense Infection Exhibit Extensive Sequence Divergence and a Subspecies-Specific Bias towards Type B N-Terminal Domains

Abstract excerpt

Human African trypanosomiasis is a neglected tropical disease primarily caused by the extracellular parasite Trypanosoma brucei gambiense . To avoid elimination by the host, these parasites repeatedly replace their variant surface glycoprotein (VSG) coat.

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