Article
Mendelian randomization study on the effect of tumor necrosis factor on schizophrenia.
Psychiatric genetics - 1 Dec 2022
Ma Ning, Wang Renxi
Abstract excerpt
OBJECTIVE: Previous observational studies have shown that the levels of tumor necrosis factor (TNF) increased in patients with schizophrenia. The present two-sample Mendelian randomization (MR) study aims to identify the causal link between TNF and schizophrenia. METHODS: To date, the largest genome-wide association study (GWAS) for TNF (n = 23 141) and for schizophrenia (53 386 cases and 77 258 controls) was...
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