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Family and case-control association study of the tumor necrosis factor-alpha (TNF-alpha) gene with schizophrenia and response to antipsychotic medication.

Psychopharmacology - 1 Oct 2006

Zai Gwyneth, Müller Daniel J, Volavka Jan, Czobor Pal, Lieberman Jeffrey A, Meltzer Herbert Y, Kennedy James L

Abstract excerpt

BACKGROUND: Dysregulation of the immune system has been suggested to play a role in the etiology of schizophrenia (SCZ). In this context, the tumor necrosis factor-alpha (TNF-alpha) is considered an interesting candidate for genetic studies as overproduction of TNF-alpha, which may be genetically modulated, can influence neuron growth and proliferation. Moreover, the TNF-alpha gene is located on chromosome...

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PMID: 16932925
DOI: 10.1007/s00213-006-0482-4

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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