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Genetic architecture of Parkinson’s disease subtypes – Review of the literature

20 Oct 2022

Abstract excerpt

The heterogeneity of Parkinson's disease (PD) has been recognized since its description by James Parkinson over 200 years ago. The complexity of motor and non-motor PD manifestations has led to many attempts of PD subtyping with different prognostic outcomes; however, the pathophysiological foundations of PD heterogeneity remain elusive. Genetic contributions to PD may be informative in understanding the...

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PMID: 36337703
DOI: 10.3389/fnagi.2022.1023574

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