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Article

GATA-3 is a proto-oncogene in T-cell lymphoproliferative neoplasms

3 Nov 2022

Abstract excerpt

Neoplasms originating from thymic T-cell progenitors and post-thymic mature T-cell subsets account for a minority of lymphoproliferative neoplasms. These T-cell derived neoplasms, while molecularly and genetically heterogeneous, exploit transcription factors and signaling pathways that are critically important in normal T-cell biology, including those implicated in antigen-, costimulatory-, and cytokine-receptor...

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PMID: 36329027
DOI: 10.1038/s41408-022-00745-y

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