Article
Oncogenic mechanisms in Burkitt lymphoma.
Cold Spring Harbor perspectives in medicine - 1 Feb 2014
Schmitz Roland, Ceribelli Michele, Pittaluga Stefania, Wright George, Staudt Louis M
Abstract excerpt
Burkitt lymphoma is a germinal center B-cell-derived cancer that was instrumental in the identification of MYC as an important human oncogene more than three decades ago. Recently, new genomics technologies have uncovered several additional oncogenic mechanisms that cooperate with MYC to create this highly aggressive cancer. The transcription factor TCF-3 is central to Burkitt lymphoma pathogenesis. TCF-3 is...
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