Article
T-cell transcription factor GATA-3 is an immunophenotypic marker of acute leukemias with T-cell differentiation.
Human pathology - 1 Jul 2017
Dorfman David M, Morgan Elizabeth A, Pelton Ashley, Unitt Christine
Abstract excerpt
T-cell transcription factor GATA-3, known to play a role in early T-cell development and in the development of T-cell neoplasms, is expressed at high levels in fetal and adult thymus, as well as in acute leukemias with T-cell differentiation, including T-lymphoblastic leukemia/lymphoma (22/22 cases), early T-cell precursor lymphoblastic leukemia (11/11 cases), and mixed-phenotype acute leukemia, T/myeloid (4/5...
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