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Article

Polymorphisms in glucose homeostasis genes are associated with cardiovascular and renal parameters in patients with diabetic nephropathy.

Annals of medicine - 1 Dec 2022

Mota-Zamorano Sonia, González Luz M, Robles Nicolás R, Valdivielso José M, Arévalo-Lorido José C, López-Gómez Juan, Gervasini Guillermo

Abstract excerpt

BACKGROUND: Diabetic nephropathy (DN) has become the major cause of end-stage kidney disease and is associated to an extremely high cardiovascular (CV) risk. METHODS: We screened 318 DN patients for 23 SNPs in four glucose transporters (SLC2A1, SLC2A2, SLC5A1 and SLC5A2) and in KCNJ11 and ABCC8, which participate in insulin secretion. Regression models were utilised to identify associations with renal parameters,...

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Share to Carotid Intima-Media Thickness
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetic Nephropathies

Share to Glomerular Filtration Rate

Share to Glucose

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 36314849
DOI: 10.1080/07853890.2022.2138531
PMCID: PMC9635471

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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