Article
Predictive role of multilocus genetic polymorphisms in cardiovascular disease and inflammation-related genes on chronic kidney disease in Type 2 diabetes--an 8-year prospective cohort analysis of 1163 patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jan 2012
Wang Ying, Luk Andrea O Y, Ma Ronald C W, So Wing-Yee, Tam Claudia H T, Ng Maggie C Y, Yang Xilin, Lam Vincent, Tong Peter C Y, Chan Juliana C N
Abstract excerpt
BACKGROUND: Chinese diabetic patients are at greater risk of developing chronic kidney disease (CKD) than Caucasian counterparts. In this hypothesis-generating study, we examined the independent and joint effects of multiple genetic variants on CKD in a prospective Chinese cohort of Type 2 diabetic patients. METHODS: Seventy-seven single-nucleotide polymorphisms (SNPs) of 54 candidate genes for cardiorenal...
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