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COMT rs4818 less common allele is associated with psychological and psychiatric worse indicators in a cohort of individuals born with cleft lip and palate.

Orthodontics & craniofacial research - 1 Aug 2023

Vieira Alexandre Rezende, Barros Mariana S, Soares Maria Sueli Marques, Lacerda Rosa Helena Wanderley

Abstract excerpt

OBJECTIVE: Individuals born with cleft lip and palate may face difficulties in speech function, nutrition, facial aesthetics, and long-term care. These difficulties may increase the risk of psychological and psychiatric diseases. This work aimed to test if the variant allele of COMT was carried more frequently among individuals that have psychological and psychiatric outcomes within a cohort of patients born with...

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PMID: 36309845
DOI: 10.1111/ocr.12619

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