Article
Genetic influence on treatment outcomes in patients with pain-related temporomandibular disorders.
Journal of oral rehabilitation - 1 Aug 2024
Zlendić Marko, Vrbanović Ema, Trošelj Koraljka Gall, Tomljanović Marko, Đerfi Kristina Vuković, Alajbeg Iva Z
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) may influence pain susceptibility and impact treatment response in pain-related temporomandibular disorders (TMDp). OBJECTIVE: Explore the role of COMT (rs4646310, rs6269, rs4818, rs4680) and OPRM1 (rs1799971) genotypes in regulating treatment response. METHODS: Sixty TMDp patients (55 females and 5 males), diagnosed with the Diagnostic Criteria for TMD (DC/TMD),...
