Article
Polymorphisms of stress-related genes and the risk of nonsyndromic cleft lip with or without cleft palate.
Birth defects research. Part A, Clinical and molecular teratology - 1 Nov 2011
Mostowska Adrianna, Hozyasz Kamil K, Wojcicka Karolina, Lianeri Margarita, Jagodzinski Pawel P
Abstract excerpt
BACKGROUND: Nonsyndromic cleft lip with or without cleft palate (NCL/P) is a common structural malformation with a complex and multifactorial etiology. It has been shown that maternal psychological stress in the periconceptional period can contribute to an increase in the risk of NCL/P affecting pregnancy. METHODS: Twenty-four single nucleotide polymorphisms of 11 stress-related genes (COMT, CRHR1, FKBP5, GABRA6,...
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