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Is catechol-O-methyltransferase gene associated with temporomandibular disorders? A systematic review and meta-analysis.

International journal of paediatric dentistry - 1 Jan 2021

Brancher João Armando, Bertoli Fernanda Mara de Paiva, Michels Bruna, Lopes-Faturri Aluhê, Pizzatto Eduardo, Losso Estela Maris, Orsi Juliana Schaia, Feltrin de Souza Juliana, Küchler Erika Calvano, Wambier Letícia Maíra

Abstract excerpt

BACKGROUND: Temporomandibular disorder (TMD) is a condition, in which multiple factors act synergistically to determine the outcome of the disorder. AIM: A systematic review and meta-analysis was conducted to evaluate the association between genetic polymorphisms in catechol-O-methyltransferase (COMT) and TMD. DESIGN: Observational studies that investigated this association were included. The risk of bias and...

Topics

Catechol O-Methyltransferase
Genotype
Humans
Pain
Polymorphism, Genetic
Temporomandibular Joint Disorders

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 32961632
DOI: 10.1111/ipd.12721

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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