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Amyloid beta and its naturally occurring N-terminal variants are potent activators of human and mouse formyl peptide receptor 1

26 Oct 2022

Abstract excerpt

evoked cell migration, which argues for a functional selectivity of different Aβ peptides. Together, these findings provide the first evidence that not only hFPR2 but also hFPR1 and hFPR3 may contribute to neuroinflammation in Alzheimer's disease through an interaction with different Aβ variants.

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PMID: 36309087
DOI: 10.1016/j.jbc.2022.102642

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

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