Article
Lack of association between interleukin 23 receptor gene polymorphisms and rheumatoid arthritis susceptibility.
Rheumatology international - 1 May 2009
Park Jeong Ha, Kim Yun Jung, Park Byung Lae, Bae Joon Seol, Shin Hyoung Doo, Bae Sang-Cheol
Abstract excerpt
The recent discovery of interleukin 23 (IL-23), its receptor, and the underlying signal transduction pathway has improved our understanding of cellular immunity. Several studies suggest that IL-23 is an essential promoter of chronic joint inflammation. In this report, we assess the possible association of interleukin 23 receptor (IL23R) polymorphisms and haplotypes with rheumatoid arthritis (RA). The study was...
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