Article
Evidence of association of interleukin-23 receptor gene polymorphisms with Egyptian rheumatoid arthritis patients.
Human immunology - 1 Jun 2015
Hamdy Gehan, Darweesh Hanan, Khattab Enas A, Fawzy Samar, Fawzy Esmat, Sheta Marwa
Abstract excerpt
BACKGROUND: The identification of additional genetic risk factor is an on-going process that will aid in the understanding of rheumatoid arthritis (RA) aetiology. A genome-wide association scan in Crohn's (CD) disease highlighted the interleukin-23 receptor (IL23R) gene as a susceptibility factor. Since the IL-23/IL-17 pathway is known to associate with other autoimmune disease, including rheumatoid arthritis and...
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