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Article

A Prism Vote method for individualized risk prediction of traits in genotype data of Multi-population.

PLoS genetics - 1 Oct 2022

Xia Xiaoxuan, Zhang Yexian, Sun Rui, Wei Yingying, Li Qi, Chong Marc Ka Chun, Wu William Ka Kei, Zee Benny Chung-Ying, Tang Hua, Wang Maggie Haitian

Abstract excerpt

Multi-population cohorts offer unprecedented opportunities for profiling disease risk in large samples, however, heterogeneous risk effects underlying complex traits across populations make integrative prediction challenging. In this study, we propose a novel Bayesian probability framework, the Prism Vote (PV), to construct risk predictions in heterogeneous genetic data. The PV views the trait of an individual as...

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PMID: 36302058
DOI: 10.1371/journal.pgen.1010443
PMCID: PMC9642904

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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