Article
Temperature Influences the Interaction between SARS-CoV-2 Spike from Omicron Subvariants and Human ACE2.
Viruses - 30 Sept 2022
Gong Shang Yu, Ding Shilei, Benlarbi Mehdi, Chen Yaozong, Vézina Dani, Marchitto Lorie, Beaudoin-Bussières Guillaume, Goyette Guillaume, Bourassa Catherine, Bo Yuxia, Medjahed Halima, Levade Inès, Pazgier Marzena, Côté Marceline, Richard Jonathan, Prévost Jérémie, Finzi Andrés
Abstract excerpt
SARS-CoV-2 continues to infect millions of people worldwide. The subvariants arising from the variant-of-concern (VOC) Omicron include BA.1, BA.1.1, BA.2, BA.2.12.1, BA.4, and BA.5. All possess multiple mutations in their Spike glycoprotein, notably in its immunogenic receptor-binding domain (RBD), and present enhanced viral transmission. The highly mutated Spike glycoproteins from these subvariants present...
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