Article
Antigenicity of the Mu (B.1.621) and A.2.5 SARS-CoV-2 Spikes.
Viruses - 14 Jan 2022
Chatterjee Debashree, Tauzin Alexandra, Laumaea Annemarie, Gong Shang Yu, Bo Yuxia, Guilbault Aurélie, Goyette Guillaume, Bourassa Catherine, Gendron-Lepage Gabrielle, Medjahed Halima, Richard Jonathan, Moreira Sandrine, Côté Marceline, Finzi Andrés
Abstract excerpt
The rapid emergence of SARS-CoV-2 variants is fueling the recent waves of the COVID-19 pandemic. Here, we assessed ACE2 binding and antigenicity of Mu (B.1.621) and A.2.5 Spikes. Both these variants carry some mutations shared by other emerging variants. Some of the pivotal mutations such as N501Y and E484K in the receptor-binding domain (RBD) detected in B.1.1.7 (Alpha), B.1.351 (Beta) and P.1 (Gamma) are now...
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