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Article

Mutational Signatures as Sensors of Environmental Exposures: Analysis of Smoking-Induced Lung Tissue Remodeling.

Biomolecules - 27 Sept 2022

Kim Yoo-Ah, Hodzic Ermin, Amgalan Bayarbaatar, Saslafsky Ariella, Wojtowicz Damian, Przytycka Teresa M

Abstract excerpt

Smoking is a widely recognized risk factor in the emergence of cancers and other lung diseases. Studies of non-cancer lung diseases typically investigate the role that smoking has in chronic changes in lungs that might predispose patients to the diseases, whereas most cancer studies focus on the mutagenic properties of smoking. Large-scale cancer analysis efforts have collected expression data from both tumor and...

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Identifiers

PMID: 36291592
DOI: 10.3390/biom12101384
PMCID: PMC9599238

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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