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Smoking-associated gene expression alterations in nasal epithelium reveal immune impairment linked to lung cancer risk

8 Apr 2024

Abstract excerpt

BACKGROUND: Lung cancer is the leading cause of cancer-related death in the world. In contrast to many other cancers, a direct connection to modifiable lifestyle risk in the form of tobacco smoke has long been established. More than 50% of all smoking-related lung cancers occur in former smokers, 40% of which occur more than 15 years after smoking cessation. Despite extensive research, the molecular processes for...

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PMID: 38589970
DOI: 10.1186/s13073-024-01317-4

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