Article
Contribution of Matrix Metalloproteinase-1 Genotypes to Colorectal Cancer in Taiwan.
Cancer genomics & proteomics - 1 Jan 2000
Wu Ming-Hsien, Yueh Te-Cheng, Chang Wen-Shin, Tsai Chia-Wen, Fu Chun-Kai, Yang Mei-Due, Yu Chien-Chih, Bau DA-Tian
Abstract excerpt
BACKGROUND/AIM: Matrix metalloproteinase-1 is responsible for extracellular matrix regulation, and its genetic role in colorectal cancer (CRC) is unclear. The aim of the study was to investigate the contribution of Matrix metalloproteinase-1 genotypes to CRC risk in Taiwan. MATERIALS AND METHODS: A total of 362 cases and 362 controls were included and their MMP-1 -1607 (rs1799705) genotypes were examined. The...
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