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Article

[Association between single nucleotide genetic polymorphisms in ABC transporter genes with drug-resistant epilepsy in the Spanish population].

Revista de neurologia - 1 Nov 2022

Nava-Cedeño D J, Alonso-Cerezo M C, Sanz-García A, Vega-Zelaya L, Gordillo-Perdomo J J, Toledo-Heras M, Pastor-Gómez J, Torres-Díaz C, Pulido-Rivas P, García-Sola R

Abstract excerpt

INTRODUCTION: Almost a third of all patients with epilepsy (30%) fail to respond to pharmacological treatment. The presence of single nucleotide polymorphisms (SNPs) in the individual may influence the variability of the response to drug treatment. The transporter hypothesis posits that the presence of SNPs in the genes encoding ABC proteins would affect the bioavailability of antiseizure drugs at the...

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Identifiers

PMID: 36285445
DOI: 10.33588/rn.7509.2022133
PMCID: PMC10280709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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