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Gene clusters linked to insulin resistance identified in a genome-wide study of the Taiwan Biobank population

14 Apr 2025

Abstract excerpt

This pioneering genome-wide association study examined surrogate markers for insulin resistance (IR) in 147,880 Taiwanese individuals using data from the Taiwan Biobank. The study focused on two IR surrogate markers: the triglyceride to high-density lipoprotein cholesterol (TG:HDL-C) ratio and the TyG index (the product of fasting plasma glucose and triglycerides). We identified genome-wide significance loci...

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PMID: 40229288
DOI: 10.1038/s41467-025-58506-x

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