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Article

A comprehensive evaluation of polygenic score and genotype imputation performances of human SNP arrays in diverse populations.

Scientific reports - 20 Oct 2022

Nguyen Dat Thanh, Tran Trang T H, Tran Mai Hoang, Tran Khai, Pham Duy, Duong Nguyen Thuy, Nguyen Quan, Vo Nam S

Abstract excerpt

Regardless of the overwhelming use of next-generation sequencing technologies, microarray-based genotyping combined with the imputation of untyped variants remains a cost-effective means to interrogate genetic variations across the human genome. This technology is widely used in genome-wide association studies (GWAS) at bio-bank scales, and more recently, in polygenic score (PGS) analysis to predict and stratify...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36266455
DOI: 10.1038/s41598-022-22215-y
PMCID: PMC9585077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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