Article
Clinical Implications of BRCA Mutations in Advanced Biliary Tract Cancer.
Oncology - 1 Jan 2023
Kim Hyera, Kim Jin Young, Park Keon Uk
Abstract excerpt
INTRODUCTION: Current standard chemotherapy for biliary tract cancer (BTC) has limited survival benefits, and the need for targeted therapies is increasing. This study investigated the genetic profiles and clinical implications of BRCA mutations in patients with advanced BTC. METHODS: Targeted high-throughput sequencing was performed on samples obtained from 25 patients with advanced BTC who had received...
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