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Article

Molecular profile of BRCA-mutated biliary tract cancers

1 Jan 2020

Abstract excerpt

Introduction Prognosis of biliary tract cancers (BTC) remains dismal and novel treatment strategies are needed to improve survival. BRCA mutations are known to occur in BTC but their frequency and the molecular landscape in which they are observed in distinct sites of BTC remain unknown. Material and methods Tumour samples from 1292 patients with BTC, comprising intrahepatic cholangiocarcinoma (IHC, n=746),...

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Share to Cholangiocarcinoma and Gallbladder Cancer Studies
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PMID: 32576609
DOI: 10.1136/esmoopen-2020-000682

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